International Law Book By Sk Kapoor Pdf 23
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International Law Book By Sk Kapoor Pdf 23
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As part of the collaborative initiative, a referral system for systematic collection and curation of baseline data is being maintained. The program collects detailed clinical information, including the signs, symptoms, and clinical investigations performed on the patient and family members. The GUaRDIAN maintains a semantically oriented framework, which relies extensively on the internationally accepted and popularly used semantic ontologies established and widely used including the human phenotype ontology . The application of such a centralized data resource is manifold. While on the one end, it not only provides a holistic view of the burden of genetic diseases in the country, it also provides immense insights into the common and rare genetic variants in different sub-populations. This would enable clinicians and policy-makers to design intervention programs including genetic education and genetic counseling.
A centralized sequencing facility has been established at the CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, which can be accessed by any collaborator in order to generate high-quality NGS sequencing data as per international standards [134,135,136], with various platforms such as Hiseq 2500 and NovaSeq 6000 (Illumina Inc. USA). A dedicated training team for both experimental and computational work necessary to perform the data capture and analysis of high-throughput sequencing data is also channelized as a part of the GUaRDIAN consortium. Investigators are free to generate sequence data on their own or from other commercial facilities that adhere to international guidelines and GUaRDIAN consortium standards. The sequencing requirements are updated and modified in accordance with the technological advancement and emerging international consensus.
GUaRDIAN has contributed to the identification of the pharmacogenetic variants in dihydropyrimidine dehydrogenase (DPYD) gene, which determines the metabolism of the commonly used anti-neoplastic drug 5-fluorouracil, in south-east Asian countries . The consortium has also undertaken international initiatives to derive the pharmacogenomic landscape in Malays  and Qatari populations [157, 158], and to identify genetic variants of Arab, Middle East, and North African populations [159, 160]. GUaRDIAN has also set up a systematic pipeline for next generation sequencing of the mitochondrial genome for clinical applications, called the mit-o-matic .
When we refer to social media, applications such as Facebook, WhatsApp, Twitter, YouTube, LinkedIn, Pinterest, and Instagram often come to mind. These applications are driven by user-generated content, and are highly influential in a myriad of settings, from purchasing/selling behaviours, entrepreneurship, political issues, to venture capitalism (Greenwood and Gopal 2015). As of April 2017, Facebook enjoys the exalted position of being the market leader of the social media world, with 1.97 billion monthly users (Statista 2017). In addition to posts, social media sites are bombarded with photo and video uploads, and according to the recent numbers, about 400 million snaps a day have been recorded on Snapchat, with around 9000 photos being shared every second (Lister 2017). While 50 million businesses are active on Facebook business pages, two million businesses are using Facebook advertising. Apparently, 88% businesses use Twitter for marketing purposes (Lister 2017).
Cluster 7: The dominant theme here is the nature and content of communication. In particular, scholars in this cluster have focused on communication and response in the face of crises (Coombs), including image restoration after a controversy (Benoit), analysis and reliability of content (Krippendorff), and the use of social media sites such as Facebook and Twitter by government agencies and non-profit organizations to engage stakeholders (Waters).
The review of studies related to this theme suggests that since 2010, IS researchers have focussed on examining the dysfunctional consequences of social media adoption, such as - addiction, stress, information overload, and others. Use behaviour was examined across a variety of platforms like Facebook, Twitter, MySpace, and Flickr. Media content, such as picture, video, and tweets have also been explored by the studies in this category.
Publications have also shown interest in investigating the effects of user-generated content on entrepreneurial behaviour. For instance, Greenwood and Gopal (2015) find that discourse in both traditional and user-generated media has a notable influence on IT firm founding rates. Lundmark et al. (2016) reveal that higher usage of Twitter, alongside follower numbers and retweets result in higher levels of under pricing for initial public offerings (IPO). Trier and Richter (2015) find that online organizational networking has many unbalanced multiplex relationships, mostly comprising of weak ties and temporal change. They attribute the uneven user contribution in social networking sites to discourse drivers and information retrievers. Schlagwein and Hu (2016) identify collaboration, broadcast, dialogue, sociability, and knowledge management as the social media types that serve varied organizational purposes. Claussen et al. (2013) study Facebook to conclude that social media networks can exercise management not only by excluding participants, but also by driving softer changes in incentive/reward systems.
The reviewed publications were also analyzed to determine the nature of the social network that were studied. Precisely 46 websites emerged, with Facebook, online communities, Twitter, Blogs and YouTube being most frequently targeted. Networks analysed by at least two or more studies have been identified in Table 5. The other networks that received attention from the reviewed publications include Ebay, Flickr, Flixster, Gtalk, microsoft, MSN Space, Patientslikeme, New York Times, TripAdvisor.com, and Boxofficemojo.com. Studies also focussed on websites related to online news, Q&A websites, discussion groups and forums, online radio and television, and medical sites such as Webmd.com.
Matook et al. (2015a) identify that there is a need to study the aspect of trust formation between individuals on social media, where no personal relationships exist (unlike sites such as Facebook). Chung et al. (2017) identify that researchers often associate the use of certain social media with young users (for instance, Maier et al. 2015b), and fail to study the usage perceptions across various ages (Vishwanath 2015). Van Osch and Steinfield (2016) suggest that future researchers should explore the potential of Enterprise Social Media to gain insights into the tools that support disentanglement of team boundary spanning. Finally, researchers have established that the lifecycle of information and communication technologies tend to be emancipatory in their infancy but eventually evolve into hegemonic tools. They warn social media policymakers to be wary of reproducing this pattern with digital media; the recommendation is to involve more citizens in the development of Internet governance framework, rather than resting decisions with the members of political or economic power (Miranda et al. 2016).
Kapur became known in Bollywood with his recurring role in the television series Khandaan. He then made his directorial debut with cult classic Masoom in 1983, before gaining widespread acclaim with Mr. India in 1987. He then gained international recognition and acclaim in 1994 with biographical film Bandit Queen, based on the infamous Indian bandit and politician Phoolan Devi, it was premiered in the directors fortnight section of the 1994 Cannes Film Festival and was screened at the Edinburgh Film Festival.
Kapur achieved further international prominence with the 1998 period film Elizabeth, a fictional account of the reign of British Queen Elizabeth I, which was nominated for seven Academy Awards. He then directed war drama film The Four Feathers (2002). In 2007, he directed Elizabeth: The Golden Age, the sequel to his 1998 Elizabeth film.
In 1998, he received international recognition for the second time after Bandit Queen, when he directed the Academy Award-winning period film Elizabeth, a fictional account of the reign of British Queen Elizabeth I nominated for seven Oscars. The 2007 sequel, Elizabeth: The Golden Age, was nominated for two Oscars. He was accused of being anti-British by British tabloids for his portrayal of the British Army in the 2002 movie The Four Feathers. However, he denied the accusations and stated that he was merely "anti-colonisation".
In an unusual role for him, Kapur provided the voice of Mohandas Gandhi in the Charkha Audiobooks title of The Story of My Experiments with Truth, alongside Nandita Das as narrator.
In 2000, he received Padma Shri, the fourth highest civilian award in India. In 2010, he served as one of the Jury Members in international competition at the 63rd Cannes Film Festival. In 2020, Kapur became the president of the Film and Television Institute of India. 076b4e4f54